Mid way between Wake Forest nc and Waynesville nc

Assuming you take I-85 > I-40, it's about 275 miles from Wake Forest to Waynesville (North Carolina). It'll take a minimum of 4.5 hours to drive with no traffic congestion or stops for fuel/food/rest. 
Statesville is roughly the halfway point, around 165 miles from Wake Forest. . There's a Hampton Inn:
https://www.hilton.com/en/hotels/svhhhhx-hampton-statesville/
Hampton Inn Statesville
A Days Inn:
https://www.wyndhamhotels.com/en-uk/days-inn/statesville-north-carolina/days-inn-by-wyndham-statesville/overview
Days Inn Statesville
A Holiday Inn Express:
https://www.ihg.com/holidayinnexpress/hotels/gb/en/statesville/snhet/hoteldetail
Holiday Inn Express & Suites Statesville, an IHG Hotel
and several other hotels.
You can find what accommodation is available for your dates listed and reviewed on the long-established and reliable https://www.booking.com