https://www.trippy.com/drive/Santa-Ana-CA-to-Portland-in-2-days I did this quick trippy itenerary for you, when we did the trip it was two weeks so for yours I focused more on the drive time than the sights. You can run the itenerary again using the link and use the edits as you like. Day 1 10:00 am start in Santa Ana drive for about 4 hoursEdit2:06 pm Paso Robles stay for about 1 hour and leave at 3:06 pm drive for about 4 hoursEdit7:00 pm Napa eat at ad hoc stay overnight at Bardessono leave the next day around 9:00 am Day 2 9:00 am leave from Bardessono drive for about 3 hoursEdit11:52 am Redding stay for about 1 hour and leave at 12:52 pm drive for about 2.5 hoursEdit3:13 pm Ashland (Oregon) stay for about 1 hour and leave at 4:13 pm drive for about 4.5 hours8:42 pm arrive in Portland
I answered a question similar to this earlier, see here. https://www.trippy.com/question/Lake-Tahoe-Best-stops-for-leisurely-drive#answerItemView_5cb3e72dc6ac18f74b6d1f04 Basically you can go I-5 or the coast. Since you are in more of a rush (and maybe don't want to engage in longer stops) I would do the coast route. Although there are tons of to do options on this route and the drive is slower, it is very scenic, so if you decided only to do really short stops it would still be very enjoyable.
Maria