what are the highway numbers to drive there
If you are on I-95 you take exit 8 onto US 278 for Hilton Head Island
US 278 is the road to take to get onto the island. There are shortcuts - From Savannah you could take US 17and SC 315 to SC 46 to US 278 instead of using I-95. Or from the north you could get off at exit 28 and take SC 462 E down to US 278. But you have to end up on US 278.