Heading to Dublin in a month for a quick two day trip. What is the best neighborhood/area to stay in so that we can walk most everywhere? We will be going to Guiness, would like to see Trinity College, the Castle, and other popular sites.
there are a good few options for you on the south side of the River Liffey. I would stay away from Temple Bar if you don't like too much noise.
Depending on your budget there are many places to recommend including The Central Hotel which is close to the Creative Quarter, Trinity City Hotel, Westin Hotels Ireland Ltd, The Westbury Hotel, Radisson Blu Royal Hotel Dublin and Jurys Inn Christchurch Dublin.
Guesthouses and B&Bs are usually concentrated further from the city centre sights.
Most of these places will leave you within easy walking distance of the main sights such as Trinity College, Dublin Castle, St Patrick's Cathedral, National Museum of Ireland - Archaeology etc. and of course Guinness Storehouse is a bit further from the centre.
Hope you enjoy your visit!
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Darren has some great suggestions and I would add Airbnb and suggest you also look at staying anywhere along the DART line (Dublin Area Rapid Transport - an electric train that runs along the coast from North county Dublin (Last stop north: Howth; a lovely fishing village with lots of nice fish restaurants) and last stop south: Greystones in Co Wicklow - another really nice little town) Many of the villages on the route have a beach and some have really nice walking routes: Killiney Dalkey Greystones Clontarf Blackrock and Howth for example. The furthest you will be away from the city is about 55 mins and some areas are as little as 5 -10 mins by train (e.g. Grand Canal Dock which has its own theatre, and is walkable to town) Accommodation may be cheaper too and you can live like a local for a couple of days!
Have a great trip.
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I'd recommend D1, D2 or D4.
You can view the various areas here: http://www.jumbletown.ie/forums/attachment.php?attachmentid=63644&stc=1&d=1302116900
Basically Dublin is split in half by the River Liffey, and there is actually a kind of constant banter going on between people from the North and the South.
Anyway, lots of the historic parts are south of the Liffey, while the more modern parts are in the North. But that's just a very vague generalisation, there's exciting spots on either side of the river.
I hope I was able to help you out, if you have any more questions, let me konw ;)
Temple Bar - it's really not that loud. We stayed at old Georgian townhouse on Eustace St the week of the Marriage Equality Referendum and that was a noisy night, and yet we got to sleep just fine (and the family I was with had a baby as well!).
The location was fantastic to see all the sights of Dublin in a week.