To reach the midway point from Tours to Nantes, you would drive for about 1 hour, 3 minutes or roughly 108 km from Nantes to the halfway stop.
The exact coordinates of the midpoint are:
47° 31' 22" N
0° 21' 19" W
The best place to meet based on recommendations from Trippy members is Saumur.
The location closest to the exact midpoint would be Saint-Sylvain-d'Anjou.
Here are some local accommodations near the midpoint:
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Q&A from Nantes to Tours:
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