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Here's a sample itinerary for a drive from Tallahassee to Florence (South Carolina). If you're planning a road trip to Florence (South Carolina), you can research locations to stop along the way. Traveling with a dog or cat? View pet-friendly stops between Tallahassee and Florence (South Carolina). Camping along the way? View RV campgrounds between Tallahassee and Florence (South Carolina). Find the best hotels, restaurants, and attractions based on the most talked about places recommended by Trippy members.
11:00 am start in Tallahassee
drive for about 1.5 hours
12:30 pm Jennings
stay for about 1 hour
and leave at 1:30 pm
drive for about 43 minutes
2:13 pm Lake City
stay for about 1 hour
and leave at 3:13 pm
drive for about 59 minutes
4:12 pm Jacksonville
stay overnight and leave the next day around 10:00 am
day 1 driving ≈ 3 hours
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10:00 am leave from Jacksonville
drive for about 2 hours
11:59 am Savannah
stay for about 2 hours
and leave at 1:59 pm
drive for about 1 hour
3:10 pm Walterboro
stay for about 1 hour
and leave at 4:10 pm
drive for about 45 minutes
4:55 pm Santee (South Carolina)
stay for about 1 hour
and leave at 5:55 pm
drive for about 1 hour
7:01 pm arrive in Florence (South Carolina)
day 2 driving ≈ 5 hours
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Your starting point is Tallahassee, Florida.
You can enter an exact street address if you want to get precise directions, but this is optional.
Since there are only 2 travelers, we assume you're driving 1 car. You can adjust the number of people traveling at the top. We assume a maximum of 4 passengers per car, but you can change the number of cars to fit your situation.
Jennings
Lake City
Jacksonville (22 answers)
questions about Jacksonville:
What's the best neighborhood in Jacksonville for a first time visitor?
Savannah (92 answers)
Forsyth Park (9 mentions)
Bonaventure Cemetery (5 mentions)
Savannah's Historic District (3 mentions)
The Pirates House Savannah GA (3 mentions)
River Street (3 mentions)
restaurants around Savannah:
Mrs. Wilkes Dining Room
Crystal Beer Parlor
The Olde Pink House
Gryphon Tea Room
Clary's Cafe
questions about Savannah:
What is your favorite under rated attraction in Savannah?
Leisurely trip to Savannah
What are fun things to do in Savannah on a budget?
Little Ones in Savannah
Art & Culture in Savannah?????
Walterboro
Santee (South Carolina)
Your final destination is Florence, South Carolina.
You can enter the exact street address of your destination, but this is optional.
This section could be endless, so rather than trying to suggest every local activity or attraction, we'll leave it open-ended.
Of course, Trippy is the perfect place to ask questions because there's an entire community of travelers talking to each other and sharing tips and advice. Trippy is where you can get answers personalized for your tastes, budgets, trip dates & more!
Click the button below to explore more questions and answers related to Florence (South Carolina).
Yes, even this step is optional, because if you're on vacation who wants the trip to end? It's okay, you can start planning your next trip!
Want to plan the trip back? Get the reverse directions for a Florence (South Carolina) to Tallahassee drive, or go to the main page to plan a new road trip.
You can also compare the travel time if you're flying or driving by calculating the distance from Tallahassee to Florence (South Carolina). Or get a full Tallahassee to Florence (South Carolina) flight plan.
Don't forget about exploring your own hometown with a staycation. You can also find some cool day trips or get away for a weekend. Maybe try typing in a faraway location like London, Hong Kong, or Sydney, and get inspired for your dream trip around the world.
And if you know Tallahassee well, please help your fellow travelers and answer their questions about Tallahassee!
This is the most common route that Trippy members have taken, but you can also explore alternate routes from Tallahassee to Florence, or check the current road conditions from Tallahassee to Florence.
