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Myrtle Beach to Gatlinburg via Cherokee (North Carolina)

driving   /   2 days   /   no pets   /   no RV

Myrtle Beach to Gatlinburg road trip planner

Here's a sample itinerary for a drive from Myrtle Beach to Gatlinburg. If you're planning a road trip to Gatlinburg, you can research locations to stop along the way. Make sure you check road conditions to double check the weather. Traveling with a dog or cat? Find pet-friendly stops. Camping along the way? Search for RV campgrounds. Find the best hotels, restaurants, and attractions based on the most talked about places recommended by Trippy members.

customize this trip
 Day 1

11:00 am  start in Myrtle Beach
drive for about 50 minutes

11:50 am  eat at Scotts BBQ
stay for about 1 hour
and leave at 12:50 pm
drive for about 50 minutes

1:41 pm  Florence (South Carolina)
stay for about 1 hour
and leave at 2:41 pm
drive for about 1.5 hours

4:01 pm  Columbia
stay overnight and leave the next day around 10:00 am

day 1 driving ≈ 3 hours
find more stops

 Day 2

10:00 am  leave from Columbia
drive for about 1 hour

11:08 am  Laurens (South Carolina)
stay for about 1 hour
and leave at 12:08 pm
drive for about 2 hours

2:14 pm  Cherokee (North Carolina)
stay for about 1 hour
and leave at 3:14 pm
drive for about 1 hour

4:17 pm  arrive in Gatlinburg

day 2 driving ≈ 4.5 hours
find more stops

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Where should I stop along the way?

Scotts BBQ

Florence (South Carolina)  (3 answers)

Columbia  (15 answers)
    Riverbanks Zoo and Garden  (2 mentions)

Laurens (South Carolina)

Cherokee (North Carolina)  (10 answers)


What are some things to do in Gatlinburg?

This section could be endless, so rather than trying to suggest every local activity or attraction, we'll leave it open-ended.

These are some of the places people talk about on Trippy:

Great Smoky Mountains  (2 mentions)

Of course, Trippy is the perfect place to ask questions because there's an entire community of travelers talking to each other and sharing tips and advice. Trippy is where you can get answers personalized for your tastes, budgets, trip dates & more!

Click the button below to explore more questions and answers related to Gatlinburg.




Do I really have to go back home?

Yes, even this step is optional, because if you're on vacation who wants the trip to end? It's okay, you can start planning your next trip!

Want to plan the trip back? Get the reverse directions for a Gatlinburg to Myrtle Beach drive, or go to the main page to plan a new road trip.

You can also compare the travel time if you're flying or driving by calculating the distance from Myrtle Beach to Gatlinburg. Or get a full Myrtle Beach to Gatlinburg flight plan.

Don't forget about exploring your own hometown with a staycation. You can also find some cool day trips or get away for a weekend. Maybe try typing in a faraway location like London, Hong Kong, or Sydney, and get inspired for your dream trip around the world.

And if you know Myrtle Beach well, please help your fellow travelers and answer their questions about Myrtle Beach!





At a Glance
without making any stops
total driving distance is 381 miles
driving time of 6 hours, 45 minutes
55 Myrtle Beach travel answers
3 Florence (South Carolina) travel answers
15 Columbia travel answers
1 Laurens (South Carolina) travel answer
10 Cherokee (North Carolina) travel answers
32 Gatlinburg travel answers





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