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Memphis to St. Louis drive

(tap on any row to expand for more details)

  Memphis
 Keiser
 Caruthersville
 Cape Girardeau
 Perryville (Missouri)
 Arnold
2 travelers   /   driving   /   2 days   /   no pets   /   no RV

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Memphis to St. Louis road trip planner

Here's a sample itinerary for a drive from Memphis to St. Louis. If you're planning a road trip to St. Louis, you can research locations to stop along the way. Traveling with a dog or cat? View pet-friendly stops between Memphis and St. Louis. Camping along the way? View RV campgrounds between Memphis and St. Louis. Find the best hotels, restaurants, and attractions based on the most talked about places recommended by Trippy members.

customize this trip
 Day 1

11:00 am  start in Memphis
drive for about 53 minutes

11:53 am  Keiser
stay for about 1 hour
and leave at 12:53 pm
drive for about 1 hour

1:53 pm  Caruthersville
stay for about 1 hour
and leave at 2:53 pm
drive for about 1.5 hours

4:17 pm  Cape Girardeau
stay overnight and leave the next day around 11:00 am

day 1 driving ≈ 3.5 hours
find more stops

 Day 2

11:00 am  leave from Cape Girardeau
drive for about 45 minutes

11:45 am  Perryville (Missouri)
stay for about 1 hour
and leave at 12:45 pm
drive for about 1 hour

1:50 pm  Arnold
stay for about 1 hour
and leave at 2:50 pm
drive for about 24 minutes

3:15 pm  arrive in St. Louis
stay at Hyatt Regency St. Louis at The Arch

day 2 driving ≈ 2 hours
find more stops

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Where does my trip begin?

Your starting point is Memphis, Tennessee.

You can enter an exact street address if you want to get precise directions, but this is optional.


How many cars do we need?

Since there are only 2 travelers, we assume you're driving 1 car. You can adjust the number of people traveling at the top. We assume a maximum of 4 passengers per car, but you can change the number of cars to fit your situation.


Where should I stop along the way?

Keiser

Caruthersville

Cape Girardeau  (3 answers)

Perryville (Missouri)

Arnold


Where does my trip end?

Your final destination is Saint Louis, Missouri.

You can enter the exact street address of your destination, but this is optional.


Where's the best place to stay in St. Louis?

Are you going straight to a hotel, or looking for a vacation rental or Airbnb?

The best resource on neighborhoods, areas, and hotels is the Trippy page on where to stay in St. Louis.

If you're looking for a quick answer, you can check out Hyatt Regency St. Louis at The Arch, which was mentioned 3 times on Trippy.

Here are some more hotels people talk about:

The Lemp Mansion  (2 mentions)

Want to research more popular hotels in St. Louis? Click the blue button below.




Where's the best place to eat in St. Louis?

Need some recommendations on somewhere to get food?

Trippy members suggest Pappy's Smokehouse, which was mentioned 8 times.

Here are some more restaurants people talk about:

Ted Drewes  (4 mentions)
Pastaria  (2 mentions)
Companion  (2 mentions)

Want to research more popular restaurants in St. Louis? Click the blue button below.




What are some things to do in St. Louis?

This section could be endless, so rather than trying to suggest every local activity or attraction, we'll leave it open-ended.

These are some of the places people talk about on Trippy:

Forest Park  (10 mentions)
St. Louis Zoo  (6 mentions)
City Museum  (5 mentions)
Gateway Arch  (4 mentions)

Of course, Trippy is the perfect place to ask questions because there's an entire community of travelers talking to each other and sharing tips and advice. Trippy is where you can get answers personalized for your tastes, budgets, trip dates & more!

For example, here are some questions people have asked about St. Louis. Click on any question to see answers from the community!

profile  Marci from Boston asked:
Great lunch places in St Louis  (6 answers)

profile  Gina from Minneapolis asked:
Good St. Louis dines?  (6 answers)

profile  Cassie from asked:
Good family vacation within 10 hours of St. Louis (not Branson)?  (5 answers)

profile  Shelby from Scottsdale asked:
Where are the best places to stay in St. Louis?  (5 answers)

profile  Katie from Los Angeles asked:
What's the best neighborhood in St. Louis for a first time visitor?  (5 answers)

Click the button below to explore more questions and answers related to St. Louis.




Do I really have to go back home?

Yes, even this step is optional, because if you're on vacation who wants the trip to end? It's okay, you can start planning your next trip!

Want to plan the trip back? Get the reverse directions for a St. Louis to Memphis drive, or go to the main page to plan a new road trip.

Looking for ideas for more destinations within driving distance of Memphis? Try searching for places within 4 hours of Memphis.

You can also compare the travel time if you're flying or driving by calculating the distance from Memphis to St. Louis. Or get a full Memphis to St. Louis flight plan.

Don't forget about exploring your own hometown with a staycation. You can also find some cool day trips or get away for a weekend. Maybe try typing in a faraway location like London, Hong Kong, or Sydney, and get inspired for your dream trip around the world.

And if you know Memphis well, please help your fellow travelers and answer their questions about Memphis!





At a Glance
without making any stops
total driving distance is 283 miles
driving time of 4 hours, 8 minutes
96 Memphis travel answers
3 Cape Girardeau travel answers
72 St. Louis travel answers





VIEW DETAILED MAP


This is the most common route that Trippy members have taken, but you can also explore alternate routes from Memphis to St. Louis.

Driving directions from Memphis to St. Louis

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