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Columbus to St. Louis via Louisville

driving   /   2 days   /   no pets   /   no RV

Columbus to St. Louis road trip planner

Here's a sample itinerary for a drive from Columbus to St. Louis. If you're planning a road trip to St. Louis, you can research locations to stop along the way. Make sure you check road conditions to double check the weather. Traveling with a dog or cat? Find pet-friendly stops. Camping along the way? Search for RV campgrounds. Find the best hotels, restaurants, and attractions based on the most talked about places recommended by Trippy members.

customize this trip
 Day 1

11:00 am  start in Columbus
drive for about 1 hour

12:08 pm  Dayton
stay for about 1 hour
and leave at 1:08 pm
drive for about 2.5 hours

3:39 pm  Louisville
stay overnight at 21C Museum Hotel
leave the next day around 10:00 am

day 1 driving ≈ 3.5 hours
find more stops

 Day 2

10:00 am  leave from 21C Museum Hotel
drive for about 2 hours

11:55 am  Evansville
stay for about 1 hour
and leave at 12:55 pm
drive for about 1.5 hours

2:27 pm  Mount Vernon (Illinois)
stay for about 1 hour
and leave at 3:27 pm
drive for about 1 hour

4:41 pm  arrive in St. Louis
stay at Hyatt Regency St. Louis at The Arch

day 2 driving ≈ 4.5 hours

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Where should I stop along the way?

Dayton  (5 answers)

Louisville  (47 answers)
    Louisville Slugger Museum & Factory  (3 mentions)
    Churchill Downs  (2 mentions)
    Muhammad Ali Center  (2 mentions)
    Fourth Street Live!  (2 mentions)
    Louisville Slugger Field  (2 mentions)
    restaurants around Louisville:
        Seviche, A Latin Restaurant
        Basa Restaurant
        Milkwood Restaurant
        Jeff Ruby's Louisville
        Hyatt Regency Louisville
    hotels around Louisville:
        21C Museum Hotel
        The Galt House Hotel And Suites
        The Brown Hotel
    questions about Louisville:
        What is your favorite restaurant in Louisville?
        What's the best neighborhood in Louisville for a first time visitor?
        Any cool things to do/places to eat in Louisville?
        Hotels to stay at during the Kentucky Derby?
        Has anyone been to Butchertown Market?

Evansville  (2 answers)
    questions about Evansville:
        What are the hip restaurants in Evansville, IN?

Mount Vernon (Illinois)  (2 answers)
    questions about Mount Vernon (Illinois):
        I need Locals Advise


Where's the best place to stay in St. Louis?

Are you going straight to a hotel, or looking for a vacation rental or Airbnb?

The best resource on neighborhoods, areas, and hotels is the Trippy page on where to stay in St. Louis.

If you're looking for a quick answer, you can check out Hyatt Regency St. Louis at The Arch, which was mentioned 3 times on Trippy.

Here are some more hotels people talk about:

The Lemp Mansion  (2 mentions)

Want to research more popular hotels in St. Louis? Click the blue button below.




Where's the best place to eat in St. Louis?

Need some recommendations on somewhere to get food?

Trippy members suggest Pappy's Smokehouse, which was mentioned 8 times.

Here are some more restaurants people talk about:

Ted Drewes  (4 mentions)
Pastaria  (2 mentions)
Companion  (2 mentions)

Want to research more popular restaurants in St. Louis? Click the blue button below.




What are some things to do in St. Louis?

This section could be endless, so rather than trying to suggest every local activity or attraction, we'll leave it open-ended.

These are some of the places people talk about on Trippy:

Forest Park  (10 mentions)
St. Louis Zoo  (6 mentions)
City Museum  (5 mentions)
Gateway Arch  (4 mentions)

Of course, Trippy is the perfect place to ask questions because there's an entire community of travelers talking to each other and sharing tips and advice. Trippy is where you can get answers personalized for your tastes, budgets, trip dates & more!

For example, here are some questions people have asked about St. Louis. Click on any question to see answers from the community!

profile  Katie from Los Angeles asked:
What is your favorite restaurant in St. Louis?  (12 answers)

profile  Gina from Minneapolis asked:
Good St. Louis dines?  (6 answers)

profile  Marci from Boston asked:
Great lunch places in St Louis  (6 answers)

profile  Cassie from asked:
Good family vacation within 10 hours of St. Louis (not Branson)?  (5 answers)

profile  Shelby from Scottsdale asked:
Where are the best places to stay in St. Louis?  (5 answers)

Click the button below to explore more questions and answers related to St. Louis.




Do I really have to go back home?

Yes, even this step is optional, because if you're on vacation who wants the trip to end? It's okay, you can start planning your next trip!

Want to plan the trip back? Get the reverse directions for a St. Louis to Columbus drive, or go to the main page to plan a new road trip.

You can also compare the travel time if you're flying or driving by calculating the distance from Columbus to St. Louis. Or get a full Columbus to St. Louis flight plan.

Don't forget about exploring your own hometown with a staycation. You can also find some cool day trips or get away for a weekend. Maybe try typing in a faraway location like London, Hong Kong, or Sydney, and get inspired for your dream trip around the world.

And if you know Columbus well, please help your fellow travelers and answer their questions about Columbus!





At a Glance
without making any stops
total driving distance is 471 miles
driving time of 7 hours, 5 minutes
39 Columbus travel answers
5 Dayton travel answers
47 Louisville travel answers
2 Evansville travel answers
2 Mount Vernon (Illinois) travel answers
93 St. Louis travel answers





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