Here's a sample itinerary for a drive from Cincinnati to St. Louis. If you're planning a road trip to St. Louis, you can research locations to stop along the way. Make sure you check road conditions to double check the weather. Traveling with a dog or cat? Find pet-friendly stops. Camping along the way? Search for RV campgrounds. Find the best hotels, restaurants, and attractions based on the most talked about places recommended by Trippy members.
10:00 am start in Cincinnati
drive for about 2 hours
11:46 am Louisville
eat at Seviche, A Latin Restaurant
stay for about 1.5 hours
and leave at 1:16 pm
drive for about 3 hours
4:06 pm Terre Haute (Indiana)
stay overnight and leave the next day around 10:00 am
day 1 driving ≈ 4.5 hours
find more stops
10:00 am leave from Terre Haute (Indiana)
drive for about 2 hours
12:12 pm Jasper (Indiana)
stay for about 1 hour
and leave at 1:12 pm
drive for about 1 hour
2:22 pm Evansville
stay for about 1 hour
and leave at 3:22 pm
drive for about 2 hours
5:26 pm Nashville (Illinois)
stay for about 1 hour
and leave at 6:26 pm
drive for about 60 minutes
7:26 pm arrive in St. Louis
eat at Pappy's Smokehouse
stay at Hyatt Regency St. Louis at The Arch
day 2 driving ≈ 6.5 hours
Louisville (63 answers)
Louisville Slugger Museum & Factory (3 mentions)
Churchill Downs (2 mentions)
Muhammad Ali Center (2 mentions)
Fourth Street Live! (2 mentions)
Louisville Slugger Field (2 mentions)
restaurants around Louisville:
Seviche, A Latin Restaurant
Basa Restaurant
Milkwood Restaurant
Jeff Ruby's Louisville
Hyatt Regency Louisville
questions about Louisville:
What's the best neighborhood in Louisville for a first time visitor?
What is your favorite restaurant in Louisville?
Any cool things to do/places to eat in Louisville?
Hotels to stay at during the Kentucky Derby?
Has anyone been to Butchertown Market?
Terre Haute (Indiana) (4 answers)
questions about Terre Haute (Indiana):
What is there to see in terre haute
Jasper (Indiana)
Evansville (5 answers)
questions about Evansville:
What are the hip restaurants in Evansville, IN?
Nashville (Illinois)
questions about Nashville (Illinois):
what hotels there
Are you going straight to a hotel, or looking for a vacation rental or Airbnb?
The best resource on neighborhoods, areas, and hotels is the Trippy page on where to stay in St. Louis.
If you're looking for a quick answer, you can check out Hyatt Regency St. Louis at The Arch, which was mentioned 3 times on Trippy.
Here are some more hotels people talk about:
Want to research more popular hotels in St. Louis? Click the blue button below.
Need some recommendations on somewhere to get food?
Trippy members suggest Pappy's Smokehouse, which was mentioned 8 times.
Here are some more restaurants people talk about:
Want to research more popular restaurants in St. Louis? Click the blue button below.
This section could be endless, so rather than trying to suggest every local activity or attraction, we'll leave it open-ended.
These are some of the places people talk about on Trippy:
Of course, Trippy is the perfect place to ask questions because there's an entire community of travelers talking to each other and sharing tips and advice. Trippy is where you can get answers personalized for your tastes, budgets, trip dates & more!
For example, here are some questions people have asked about St. Louis. Click on any question to see answers from the community!
Katie from Los Angeles asked:
What is your favorite restaurant in St. Louis? (15 answers)
Gina from Minneapolis asked:
Good St. Louis dines? (6 answers)
Marci from Boston asked:
Great lunch places in St Louis (6 answers)
Cassie from asked:
Good family vacation within 10 hours of St. Louis (not Branson)? (5 answers)
Shelby from Scottsdale asked:
Where are the best places to stay in St. Louis? (5 answers)
Click the button below to explore more questions and answers related to St. Louis.
Yes, even this step is optional, because if you're on vacation who wants the trip to end? It's okay, you can start planning your next trip!
Want to plan the trip back? Get the reverse directions for a St. Louis to Cincinnati drive, or go to the main page to plan a new road trip.
You can also compare the travel time if you're flying or driving by calculating the distance from Cincinnati to St. Louis. Or get a full Cincinnati to St. Louis flight plan.
Don't forget about exploring your own hometown with a staycation. You can also find some cool day trips or get away for a weekend. Maybe try typing in a faraway location like London, Hong Kong, or Sydney, and get inspired for your dream trip around the world.
And if you know Cincinnati well, please help your fellow travelers and answer their questions about Cincinnati!